BDBM50099123 5-Hexyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trione::CHEMBL176832

SMILES CCCCCCC1(C(=O)NC(=O)NC1=O)c1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=CQGUKDZSAPDCJL-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50099123   

TargetMatrix metalloproteinase-9(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099123(5-Hexyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trio...)
Affinity DataIC50: 18nMAssay Description:Inhibition of Gelatinase B, matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099123(5-Hexyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trio...)
Affinity DataIC50: 21nMAssay Description:Inhibition of Gelatinase A, matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099123(5-Hexyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trio...)
Affinity DataIC50: 78nMAssay Description:Inhibition of collagenase-3, Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099123(5-Hexyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trio...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human neutrophil collagenase-I, Matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099123(5-Hexyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trio...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099123(5-Hexyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trio...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099123(5-Hexyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trio...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of matrilysin, Matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed