BDBM50099264 3-(1-Methyl-piperidin-3-yl)-2-phenyl-1H-indole::3-(1-Methylpiperidin-3-yl)-2-phenyl-1H-indole::CHEMBL43819

SMILES CN1CCCC(C1)c1c([nH]c2ccccc12)-c1ccccc1

InChI Key InChIKey=JRFXDRYERZNJFJ-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50099264   

Target5-hydroxytryptamine receptor 2A(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50099264(3-(1-Methylpiperidin-3-yl)-2-phenyl-1H-indole | 3-...)
Affinity DataKi:  4.70nMAssay Description:Ability to displace [3H]ketanserin binding to human 5-hydroxytryptamine 2A receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50099264(3-(1-Methylpiperidin-3-yl)-2-phenyl-1H-indole | 3-...)
Affinity DataKi:  28nMAssay Description:Ability to displace [3H]spiperone binding to CHO cells stably expressing dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50099264(3-(1-Methylpiperidin-3-yl)-2-phenyl-1H-indole | 3-...)
Affinity DataKi:  150nMAssay Description:Ability to displace [3H]mesulergine binding to human 5-hydroxytryptamine 2C receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50099264(3-(1-Methylpiperidin-3-yl)-2-phenyl-1H-indole | 3-...)
Affinity DataKi:  9.60E+3nMAssay Description:Inhibition of human ERG channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50099264(3-(1-Methylpiperidin-3-yl)-2-phenyl-1H-indole | 3-...)
Affinity DataKi:  9.60E+3nMAssay Description:Displacement of [3H]dofetilide from HEK cells expressing hERG voltage dependent IKr potassium channel Kv11.1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed