BDBM50099294 5-[4-(4-chlorophenyl)-1-methyl-(3R,4S)-hexahydro-3-pyridinylcarbonyloxy]pentyl 4-(4-chlorophenyl)-1-methyl-(3R,4S)-hexahydro-3-pyridinecarboxylate::CHEMBL42203

SMILES CN1CC[C@@H]([C@H](C1)C(=O)OCCCCCOC(=O)[C@H]1CN(C)CC[C@@H]1c1ccc(Cl)cc1)c1ccc(Cl)cc1

InChI Key InChIKey=CVMHORUIZZDBSL-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50099294   

TargetSodium-dependent serotonin transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50099294(5-[4-(4-chlorophenyl)-1-methyl-(3R,4S)-hexahydro-3...)
Affinity DataKi:  25nMAssay Description:Inhibition of high affinity serotonin uptake into rat synaptosomes using [3H]5-HTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50099294(5-[4-(4-chlorophenyl)-1-methyl-(3R,4S)-hexahydro-3...)
Affinity DataKi:  56nMAssay Description:Inhibition of high affinity DA uptake into rat synaptosomes using [3H]DAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50099294(5-[4-(4-chlorophenyl)-1-methyl-(3R,4S)-hexahydro-3...)
Affinity DataKi:  64nMAssay Description:Displacement of [3H]mazindol binding to dopamine transporter (DAT) in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50099294(5-[4-(4-chlorophenyl)-1-methyl-(3R,4S)-hexahydro-3...)
Affinity DataKi:  182nMAssay Description:Ability to inhibit high affinity uptake of norepinephrine transporter into the nerve endings of rat synaptosomes using [3H]NE as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed