BDBM50099295 4-(4-Chloro-phenyl)-1-methyl-piperidine-3-carboxylic acid (5-benzoylamino-pentyl)-amide::CHEMBL40196

SMILES CN1CC[C@@H]([C@H](C1)C(=O)NCCCCCNC(=O)c1ccccc1)c1ccc(Cl)cc1

InChI Key InChIKey=ARQQAWGLHSVKJB-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50099295   

TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50099295(4-(4-Chloro-phenyl)-1-methyl-piperidine-3-carboxyl...)
Affinity DataKi:  409nMAssay Description:Displacement of [3H]mazindol binding to dopamine transporter (DAT) in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50099295(4-(4-Chloro-phenyl)-1-methyl-piperidine-3-carboxyl...)
Affinity DataKi:  465nMAssay Description:Inhibition of high affinity DA uptake into rat synaptosomes using [3H]DAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50099295(4-(4-Chloro-phenyl)-1-methyl-piperidine-3-carboxyl...)
Affinity DataKi:  494nMAssay Description:Inhibition of high affinity serotonin uptake into rat synaptosomes using [3H]5-HTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50099295(4-(4-Chloro-phenyl)-1-methyl-piperidine-3-carboxyl...)
Affinity DataKi:  1.20E+3nMAssay Description:Ability to inhibit high affinity uptake of norepinephrine transporter into the nerve endings of rat synaptosomes using [3H]NE as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed