BDBM50099328 2-(Biphenyl-4-yloxy)-4-[5-(4-fluoro-phenyl)-3-piperidin-4-yl-3H-imidazol-4-yl]-pyrimidine::CHEMBL14187

SMILES Fc1ccc(cc1)-c1ncn(C2CCNCC2)c1-c1ccnc(Oc2ccc(cc2)-c2ccccc2)n1

InChI Key InChIKey=WHARNYOKNQYQGR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50099328   

TargetMitogen-activated protein kinase 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50099328(2-(Biphenyl-4-yloxy)-4-[5-(4-fluoro-phenyl)-3-pipe...)
Affinity DataIC50: 60nMAssay Description:Inhibitory concentration against mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50099328(2-(Biphenyl-4-yloxy)-4-[5-(4-fluoro-phenyl)-3-pipe...)
Affinity DataIC50: 60nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed