BDBM50099524 3-[5-Chloro-2-(4-chloro-phenyl)-1H-indol-3-yl]-1-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propan-1-one::CHEMBL277880

SMILES COc1ccccc1N1CCN(CC1)C(=O)CCc1c([nH]c2ccc(Cl)cc12)-c1ccc(Cl)cc1

InChI Key InChIKey=NRENMILFPDPNFE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50099524   

TargetSubstance-P receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50099524(3-[5-Chloro-2-(4-chloro-phenyl)-1H-indol-3-yl]-1-[...)
Affinity DataIC50: 0.890nMAssay Description:Tested for displacement of [125I]-labeled substance P from cloned hNK1 receptor expressed in CHO cells at 100 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50099524(3-[5-Chloro-2-(4-chloro-phenyl)-1H-indol-3-yl]-1-[...)
Affinity DataIC50: 0.890nMAssay Description:Concentration required for displacement of [125I]-labeled substance P from cloned hNK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed