BDBM50099629 3-(4-Isopropyl-piperazin-1-ylmethyl)-2-phenyl-quinoline-4-carboxylic acid (1-ethyl-propyl)-amide::CHEMBL297086

SMILES CCC(CC)NC(=O)c1c(CN2CCN(CC2)C(C)C)c(nc2ccccc12)-c1ccccc1

InChI Key InChIKey=PLCGOOJEDMEMOS-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50099629   

TargetSubstance-K receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099629(3-(4-Isopropyl-piperazin-1-ylmethyl)-2-phenyl-quin...)
Affinity DataKi:  18.5nMAssay Description:Displacement of [125 I]-NKA binding to tachykinin receptor 2 in CHO membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099629(3-(4-Isopropyl-piperazin-1-ylmethyl)-2-phenyl-quin...)
Affinity DataKi:  1.21E+3nMAssay Description:Displacement of [125 I]-[MePhe]-NKB binding to hNK-3-CHO (Chinese hamster ovary) membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed