BDBM50099662 CHEMBL3319481

SMILES COc1ccc(C[C@H](NC(=O)[C@H](C)NC(=O)CN2CCOCC2)C(=O)N[C@@H](CC2CCCCC2)C(=O)[C@@]2(C)CO2)cc1

InChI Key InChIKey=UHNYITHLNFUAIN-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50099662   

TargetProteasome subunit beta type-8(Human)
Leiden Institute of Chemistry and Netherlands Proteomics Centre

Curated by ChEMBL
LigandPNGBDBM50099662(CHEMBL3319481)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of proteasome subunit beta-5i in human Raji cells using BODIPY-NC005 by fluorescent densitometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetProteasome subunit beta type-9(Human)
Leiden Institute of Chemistry and Netherlands Proteomics Centre

Curated by ChEMBL
LigandPNGBDBM50099662(CHEMBL3319481)
Affinity DataIC50: 300nMAssay Description:Inhibition of proteasome subunit beta-1i in human Raji cells using BODIPY- epoxomicin by fluorescent densitometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetProteasome subunit beta type-10(Human)
Leiden Institute of Chemistry and Netherlands Proteomics Centre

Curated by ChEMBL
LigandPNGBDBM50099662(CHEMBL3319481)
Affinity DataIC50: 410nMAssay Description:Inhibition of proteasome subunit beta-2i in human Raji cells using BODIPY- epoxomicin by fluorescent densitometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetProteasome subunit beta type-8(Human)
Leiden Institute of Chemistry and Netherlands Proteomics Centre

Curated by ChEMBL
LigandPNGBDBM50099662(CHEMBL3319481)
Affinity DataIC50: 44nMAssay Description:Inhibition of proteasome subunit beta-5i in human RPMI8226 cells using BODIPY-NC005 by fluorescent densitometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetProteasome subunit beta type-9(Human)
Leiden Institute of Chemistry and Netherlands Proteomics Centre

Curated by ChEMBL
LigandPNGBDBM50099662(CHEMBL3319481)
Affinity DataIC50: 370nMAssay Description:Inhibition of proteasome subunit beta-1i in human RPMI8226 cells using BODIPY-NC001 by fluorescent densitometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetProteasome subunit beta type-10(Human)
Leiden Institute of Chemistry and Netherlands Proteomics Centre

Curated by ChEMBL
LigandPNGBDBM50099662(CHEMBL3319481)
Affinity DataIC50: 900nMAssay Description:Inhibition of proteasome subunit beta-2i in human RPMI8226 cells using BODIPY-epoxomicin by fluorescent densitometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed