BDBM50099954 CHEMBL3319605
SMILES CCCCCCC(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]1(CO[Si](C)(C)C(C)(C)C)CO1
InChI Key InChIKey=OHYPIFPQEYUPDQ-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50099954
TargetProteasome subunit beta type-9(Human)
Leiden Institute of Chemistry and Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute of Chemistry and Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: 104nMAssay Description:Inhibition of proteasome subunit beta-1i in human Raji cells using BODIPY- epoxomicin by fluorescent densitometryMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-10(Human)
Leiden Institute of Chemistry and Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute of Chemistry and Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of proteasome subunit beta-2i in human Raji cells using BODIPY- epoxomicin by fluorescent densitometryMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-9(Human)
Leiden Institute of Chemistry and Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute of Chemistry and Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of purified human 20S immunoproteasome beta1 subunit using Ac-Pro-Ala-Leu-AMC as substrate pretreated for 1 hr followed by substrate addit...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 20S proteasome beta5 subunit in human RPMI8226 cell lysate using Suc-LLVY-AMC as substrate pretreated for 1 hr followed by substrate ad...More data for this Ligand-Target Pair