BDBM50099995 4-((1-(3-phenoxybenzyl)-1H-imidazol-5-yl)methyl)-1-(4-(trifluoromethyl)phenyl)piperazin-2-one::4-[3-(3-Phenoxy-benzyl)-3H-imidazol-4-ylmethyl]-1-(4-trifluoromethyl-phenyl)-piperazin-2-one::CHEMBL31610

SMILES FC(F)(F)c1ccc(cc1)N1CCN(Cc2cncn2Cc2cccc(Oc3ccccc3)c2)CC1=O

InChI Key InChIKey=HBYRYAHMXSFRDA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50099995   

LigandPNGBDBM50099995(4-[3-(3-Phenoxy-benzyl)-3H-imidazol-4-ylmethyl]-1-...)
Affinity DataIC50: 155nMAssay Description:In vitro inhibition against human Geranylgeranyl transferase type I catalyzed by incorporation of [3H]- GGPP (geranylgeranyl pyrophosphate) into biot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50099995(4-[3-(3-Phenoxy-benzyl)-3H-imidazol-4-ylmethyl]-1-...)
Affinity DataIC50: 5.77E+3nMAssay Description:In vitro inhibition against human Farnesyltransferase catalyzed by incorporation of [3H]- FPP into recombinant Ras-CVIMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed