BDBM50100414 1-(4-Hydroxy-5-hydroxymethyl-3-octyloxy-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione::BDBM50206490::CHEMBL400411

SMILES CCCCCCCCO[C@H]1[C@H](O)[C@@H](CO)O[C@H]1n1cc(C)c(=O)[nH]c1=O

InChI Key InChIKey=KSJKYOFITYMQNA-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50100414   

TargetThymidine kinase(HHV-1)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50100414(CHEMBL400411 | BDBM50206490 | 1-(4-Hydroxy-5-hydro...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibitory concentration against Herpes simplex virus type 1 thymidine kinase(HSV-1 TK)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetDeoxynucleoside kinase(Fruit fly)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50100414(CHEMBL400411 | BDBM50206490 | 1-(4-Hydroxy-5-hydro...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibitory concentration against Drosophila melanogaster deoxyribonucleoside kinase (Dm-dNK)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetThymidine kinase, cytosolic(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50100414(CHEMBL400411 | BDBM50206490 | 1-(4-Hydroxy-5-hydro...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibitory concentration against cytosolic thymidine kinase (TK-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetThymidine kinase(HHV-3)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50100414(CHEMBL400411 | BDBM50206490 | 1-(4-Hydroxy-5-hydro...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibitory concentration against Varicella- zoster virus thymidine kinase(VZV TK)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50100414(CHEMBL400411 | BDBM50206490 | 1-(4-Hydroxy-5-hydro...)
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibitory concentration against mitochondrial thymidine kinase (TK-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50100414(CHEMBL400411 | BDBM50206490 | 1-(4-Hydroxy-5-hydro...)
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of human TK2 assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetDeoxynucleoside kinase(Fruit fly)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50100414(CHEMBL400411 | BDBM50206490 | 1-(4-Hydroxy-5-hydro...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of Drosophila melanogaster dNK assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetThymidine kinase(HHV-1)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50100414(CHEMBL400411 | BDBM50206490 | 1-(4-Hydroxy-5-hydro...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of HSV1 TK assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetThymidine kinase, cytosolic(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50100414(CHEMBL400411 | BDBM50206490 | 1-(4-Hydroxy-5-hydro...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human TK1 assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetThymidine kinase(HHV-3)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50100414(CHEMBL400411 | BDBM50206490 | 1-(4-Hydroxy-5-hydro...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of VZV TK assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed