BDBM50100714 5-(7-Aza-bicyclo[2.2.1]hept-2-yl)-pyridin-2-ol::CHEMBL54585

SMILES O=c1ccc(c[nH]1)C1CC2CCC1N2

InChI Key

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50100714   

TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50100714(5-(7-Aza-bicyclo[2.2.1]hept-2-yl)-pyridin-2-ol | C...)
Affinity DataKi: >100nMAssay Description:Binding affinity towards rat Nicotinic acetylcholine receptor alpha3-beta2 expressed in Xenopus oocytes using [3H]epibatidine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-2/beta-2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50100714(5-(7-Aza-bicyclo[2.2.1]hept-2-yl)-pyridin-2-ol | C...)
Affinity DataKi: >100nMAssay Description:Binding affinity towards rat alpha2-beta2 neuronal nAChR expressed in Xenopus oocytes using [3H]epibatidine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50100714(5-(7-Aza-bicyclo[2.2.1]hept-2-yl)-pyridin-2-ol | C...)
Affinity DataKi:  107nMAssay Description:Inhibition of [3H]pibatidine binding at the nicotinic acetylcholine receptor alpha4-beta2 in male rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50100714(5-(7-Aza-bicyclo[2.2.1]hept-2-yl)-pyridin-2-ol | C...)
Affinity DataKi:  107nMAssay Description:Inhibition of [3H]nicotine binding to Nicotinic acetylcholine receptor alpha4-beta2 from rat membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed