BDBM50100871 (Z)-1-(benzo[d]oxazol-2-yl)octadec-9-en-1-one::(Z)-1-Benzooxazol-2-yl-octadec-9-en-1-one::1-Benzooxazol-2-yl-nonadec-10-en-2-one::CHEMBL285678

SMILES CCCCCCCC\C=C/CCCCCCCC(=O)c1nc2ccccc2o1

InChI Key InChIKey=APIPEDDJLOMNRC-UHFFFAOYSA-N

Data  7 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50100871   

TargetFatty-acid amide hydrolase 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50100871(1-Benzooxazol-2-yl-nonadec-10-en-2-one | (Z)-1-Ben...)
Affinity DataKi:  73nMAssay Description:Inhibition of human recombinant FAAHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50100871(1-Benzooxazol-2-yl-nonadec-10-en-2-one | (Z)-1-Ben...)
Affinity DataKi:  150nMAssay Description:Inhibitory activity against fatty acid amide hydrolase (FAAH)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50100871(1-Benzooxazol-2-yl-nonadec-10-en-2-one | (Z)-1-Ben...)
Affinity DataKi:  370nMAssay Description:Inhibitor affinity towards enzymes of class serine hydrolase was determined using biotin or fluorescent as radioligand (FP-biotin or FP-Rh)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50100871(1-Benzooxazol-2-yl-nonadec-10-en-2-one | (Z)-1-Ben...)
Affinity DataKi:  370nMAssay Description:Inhibition of rat FAAH assessed as conversion [14]C-oleamide to oleic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50100871(1-Benzooxazol-2-yl-nonadec-10-en-2-one | (Z)-1-Ben...)
Affinity DataKi:  370nMAssay Description:Inhibition of rat FAAH assessed as reduction in [14C]oleamide conversion to oleic acid by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50100871(1-Benzooxazol-2-yl-nonadec-10-en-2-one | (Z)-1-Ben...)
Affinity DataKi:  370nMAssay Description:Inhibition of rat FAAHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50100871(1-Benzooxazol-2-yl-nonadec-10-en-2-one | (Z)-1-Ben...)
Affinity DataKi:  370nMAssay Description:Inhibitory constant determined against recombinant Fatty-acid amide hydrolase from rat expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50100871(1-Benzooxazol-2-yl-nonadec-10-en-2-one | (Z)-1-Ben...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration of fatty acid amide hydrolase using FP-Rh radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLiver carboxylesterase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50100871(1-Benzooxazol-2-yl-nonadec-10-en-2-one | (Z)-1-Ben...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against Triacylglycerol hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50100871(1-Benzooxazol-2-yl-nonadec-10-en-2-one | (Z)-1-Ben...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against Fatty-acid amide hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLiver carboxylesterase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50100871(1-Benzooxazol-2-yl-nonadec-10-en-2-one | (Z)-1-Ben...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration of triacylgylcerol hydrolase using FP-Rh radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed