BDBM50100898 CHEMBL41928::N-{2-[(4'-cyano-1,1'-biphenyl-4-yl)oxy]ethyl}-N'-hydroxyurea

SMILES ONC(=O)NCCOc1ccc(cc1)-c1ccc(cc1)C#N

InChI Key InChIKey=YBEJDLYIFZAISG-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50100898   

TargetStromelysin-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100898(N-{2-[(4'-cyano-1,1'-biphenyl-4-yl)oxy]ethyl}-N'-h...)
Affinity DataIC50: 8.00E+4nMAssay Description:In vitro inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100898(N-{2-[(4'-cyano-1,1'-biphenyl-4-yl)oxy]ethyl}-N'-h...)
Affinity DataIC50: 5.00E+4nMAssay Description:In vitro inhibition of Matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100898(N-{2-[(4'-cyano-1,1'-biphenyl-4-yl)oxy]ethyl}-N'-h...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibition of Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100898(N-{2-[(4'-cyano-1,1'-biphenyl-4-yl)oxy]ethyl}-N'-h...)
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibitory activity against MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100898(N-{2-[(4'-cyano-1,1'-biphenyl-4-yl)oxy]ethyl}-N'-h...)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibitory activity against MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50100898(N-{2-[(4'-cyano-1,1'-biphenyl-4-yl)oxy]ethyl}-N'-h...)
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibitory activity against MMP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed