BDBM50100905 CHEMBL288510::N-[1-(4'-Cyano-biphenyl-4-yloxymethyl)-3-(4,4-dimethyl-2,5-dioxo-imidazolidin-1-yl)-propyl]-N-hydroxy-formamide

SMILES CC1(C)NC(=O)N(CCC(COc2ccc(cc2)-c2ccc(cc2)C#N)N(O)C=O)C1=O

InChI Key InChIKey=VKALTFMIUSHHED-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50100905   

Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100905(N-[1-(4'-Cyano-biphenyl-4-yloxymethyl)-3-(4,4-dime...)
Affinity DataIC50: 6.90E+3nMAssay Description:In vitro inhibition of Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100905(N-[1-(4'-Cyano-biphenyl-4-yloxymethyl)-3-(4,4-dime...)
Affinity DataIC50: 3.50E+4nMAssay Description:In vitro inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100905(N-[1-(4'-Cyano-biphenyl-4-yloxymethyl)-3-(4,4-dime...)
Affinity DataIC50: 1.40E+7nMAssay Description:In vitro inhibition of Matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed