BDBM50100909 CHEMBL290457::N-[1-(4'-Cyano-biphenyl-4-yloxymethyl)-3-(3,4,4-trimethyl-2,5-dioxo-imidazolidin-1-yl)-propyl]-N-hydroxy-formamide

SMILES CN1C(=O)N(CCC(COc2ccc(cc2)-c2ccc(cc2)C#N)N(O)C=O)C(=O)C1(C)C

InChI Key InChIKey=RNHVOKXLHUNLLK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50100909   

TargetStromelysin-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100909(N-[1-(4'-Cyano-biphenyl-4-yloxymethyl)-3-(3,4,4-tr...)
Affinity DataIC50: 1.70E+4nMAssay Description:In vitro inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100909(N-[1-(4'-Cyano-biphenyl-4-yloxymethyl)-3-(3,4,4-tr...)
Affinity DataIC50: 4.50E+4nMAssay Description:In vitro inhibition of Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100909(N-[1-(4'-Cyano-biphenyl-4-yloxymethyl)-3-(3,4,4-tr...)
Affinity DataIC50: 1.00E+7nMAssay Description:In vitro inhibition of Matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed