BDBM50100910 CHEMBL43026::N-{2-[(4'-cyano-1,1'-biphenyl-4-yl)oxy]ethyl}-N-hydroxyurea

SMILES NC(=O)N(O)CCOc1ccc(cc1)-c1ccc(cc1)C#N

InChI Key InChIKey=GMIPYLIWDLRSEB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50100910   

Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100910(N-{2-[(4'-cyano-1,1'-biphenyl-4-yl)oxy]ethyl}-N-hy...)
Affinity DataIC50: 3.50E+4nMAssay Description:In vitro inhibition of Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100910(N-{2-[(4'-cyano-1,1'-biphenyl-4-yl)oxy]ethyl}-N-hy...)
Affinity DataIC50: 5.00E+4nMAssay Description:In vitro inhibition of Matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100910(N-{2-[(4'-cyano-1,1'-biphenyl-4-yl)oxy]ethyl}-N-hy...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed