BDBM50100917 CHEMBL288592::N-[1-(4'-Cyano-biphenyl-4-yloxymethyl)-2-(3-ethyl-4,4-dimethyl-2,5-dioxo-imidazolidin-1-yl)-ethyl]-N-hydroxy-formamide

SMILES CCN1C(=O)N(CC(COc2ccc(cc2)-c2ccc(cc2)C#N)N(O)C=O)C(=O)C1(C)C

InChI Key InChIKey=XJIQVSMHQQCBEO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50100917   

Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100917(N-[1-(4'-Cyano-biphenyl-4-yloxymethyl)-2-(3-ethyl-...)
Affinity DataIC50: 1.20E+4nMAssay Description:In vitro inhibition of Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100917(N-[1-(4'-Cyano-biphenyl-4-yloxymethyl)-2-(3-ethyl-...)
Affinity DataIC50: 2.70E+4nMAssay Description:In vitro inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100917(N-[1-(4'-Cyano-biphenyl-4-yloxymethyl)-2-(3-ethyl-...)
Affinity DataIC50: 2.40E+6nMAssay Description:In vitro inhibition of Matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed