BDBM50100918 CHEMBL41102::N-[1-(4'-Cyano-biphenyl-4-yloxymethyl)-2-(4,4-dimethyl-2,5-dioxo-imidazolidin-1-yl)-ethyl]-N-hydroxy-formamide

SMILES CC1(C)NC(=O)N(CC(COc2ccc(cc2)-c2ccc(cc2)C#N)N(O)C=O)C1=O

InChI Key InChIKey=UZBOAJFAUCURIC-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50100918   

Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100918(N-[1-(4'-Cyano-biphenyl-4-yloxymethyl)-2-(4,4-dime...)
Affinity DataIC50: 8nMAssay Description:In vitro inhibition of human Matrix metalloprotease-2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100918(N-[1-(4'-Cyano-biphenyl-4-yloxymethyl)-2-(4,4-dime...)
Affinity DataIC50: 2.10E+3nMAssay Description:In vitro inhibition of human Matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100918(N-[1-(4'-Cyano-biphenyl-4-yloxymethyl)-2-(4,4-dime...)
Affinity DataIC50: 7.80E+3nMAssay Description:In vitro inhibition of Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100918(N-[1-(4'-Cyano-biphenyl-4-yloxymethyl)-2-(4,4-dime...)
Affinity DataIC50: 2.40E+4nMAssay Description:In vitro inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100918(N-[1-(4'-Cyano-biphenyl-4-yloxymethyl)-2-(4,4-dime...)
Affinity DataIC50: 2.10E+6nMAssay Description:In vitro inhibition of Matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed