BDBM50100923 CHEMBL41943::N-[(R)-2-(4,4-Dimethyl-2,5-dioxo-imidazolidin-1-yl)-1-(4'-trifluoromethoxy-biphenyl-4-yloxymethyl)-ethyl]-N-hydroxy-formamide

SMILES CC1(C)NC(=O)N(C[C@H](COc2ccc(cc2)-c2ccc(OC(F)(F)F)cc2)N(O)C=O)C1=O

InChI Key InChIKey=IIHFBHZWJNGWRC-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50100923   

Target72 kDa type IV collagenase(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50100923(N-[(R)-2-(4,4-Dimethyl-2,5-dioxo-imidazolidin-1-yl...)
Affinity DataIC50: 180nMAssay Description:Inhibition of MMP-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50100923(N-[(R)-2-(4,4-Dimethyl-2,5-dioxo-imidazolidin-1-yl...)
Affinity DataIC50: 180nMAssay Description:In vitro inhibition of human Matrix metalloprotease-2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50100923(N-[(R)-2-(4,4-Dimethyl-2,5-dioxo-imidazolidin-1-yl...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of MMP-9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50100923(N-[(R)-2-(4,4-Dimethyl-2,5-dioxo-imidazolidin-1-yl...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100923(N-[(R)-2-(4,4-Dimethyl-2,5-dioxo-imidazolidin-1-yl...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100923(N-[(R)-2-(4,4-Dimethyl-2,5-dioxo-imidazolidin-1-yl...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of MMP-3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100923(N-[(R)-2-(4,4-Dimethyl-2,5-dioxo-imidazolidin-1-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of human Matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100923(N-[(R)-2-(4,4-Dimethyl-2,5-dioxo-imidazolidin-1-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MMP-1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetMatrilysin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100923(N-[(R)-2-(4,4-Dimethyl-2,5-dioxo-imidazolidin-1-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100923(N-[(R)-2-(4,4-Dimethyl-2,5-dioxo-imidazolidin-1-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MMP-7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed