BDBM50100931 CHEMBL41324::N-Hydroxy-N-[1-(4'-methyl-biphenyl-4-yloxymethyl)-2-(3,4,4-trimethyl-2,5-dioxo-imidazolidin-1-yl)-ethyl]-formamide

SMILES CN1C(=O)N(CC(COc2ccc(cc2)-c2ccc(C)cc2)N(O)C=O)C(=O)C1(C)C

InChI Key InChIKey=KLPXBGLTDZNLHF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50100931   

Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100931(N-Hydroxy-N-[1-(4'-methyl-biphenyl-4-yloxymethyl)-...)
Affinity DataIC50: 20nMAssay Description:In vitro inhibition of human Matrix metalloprotease-2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100931(N-Hydroxy-N-[1-(4'-methyl-biphenyl-4-yloxymethyl)-...)
Affinity DataIC50: 1.60E+3nMAssay Description:In vitro inhibition of human Matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed