BDBM50100999 1,1,1-Trifluoro-3-[(3-phenoxy-phenyl)-(3-thiophen-2-yl-benzyl)-amino]-propan-2-ol::1,1,1-trifluoro-3-((3-phenoxyphenyl)(3-(thiophen-2-yl)benzyl)amino)propan-2-ol::3-((3-(thiophen-2-yl)benzyl)(3-phenoxyphenyl)amino)-1,1,1-trifluoropropan-2-ol::CHEMBL40419

SMILES OC(CN(Cc1cccc(c1)-c1cccs1)c1cccc(Oc2ccccc2)c1)C(F)(F)F

InChI Key InChIKey=ICFMDJMXVHQANS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50100999   

TargetCholesteryl ester transfer protein(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50100999(3-((3-(thiophen-2-yl)benzyl)(3-phenoxyphenyl)amino...)
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of recombinant human CETP mediated transfer of [3H]cholesteryl ester from HDL to LDLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50100999(3-((3-(thiophen-2-yl)benzyl)(3-phenoxyphenyl)amino...)
Affinity DataIC50: 8.30E+4nMAssay Description:In vitro human CETP inhibitory activity assessed by measuring the rate of [3H]cholesteryl ester ([3H]CE) from HDL donor particles to LDL acceptor par...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50100999(3-((3-(thiophen-2-yl)benzyl)(3-phenoxyphenyl)amino...)
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of CETPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Rabbit)
Al-Zaytoonah Private University of Jordan

Curated by ChEMBL
LigandPNGBDBM50100999(3-((3-(thiophen-2-yl)benzyl)(3-phenoxyphenyl)amino...)
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of CETP in rabbit serum after 1 hr by fluorescent cholesteryl esters transfer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed