BDBM50101000 3-((biphenyl-3-ylmethyl)(3-phenoxyphenyl)amino)-1,1,1-trifluoropropan-2-ol::3-[Biphenyl-3-ylmethyl-(3-phenoxy-phenyl)-amino]-1,1,1-trifluoro-propan-2-ol::CHEMBL416620

SMILES OC(CN(Cc1cccc(c1)-c1ccccc1)c1cccc(Oc2ccccc2)c1)C(F)(F)F

InChI Key InChIKey=MGMFJYCNNUVIPK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50101000   

TargetCholesteryl ester transfer protein(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50101000(3-((biphenyl-3-ylmethyl)(3-phenoxyphenyl)amino)-1,...)
Affinity DataIC50: 4.70E+4nMAssay Description:In vitro human CETP inhibitory activity assessed by measuring the rate of [3H]cholesteryl ester ([3H]CE) from HDL donor particles to LDL acceptor par...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50101000(3-((biphenyl-3-ylmethyl)(3-phenoxyphenyl)amino)-1,...)
Affinity DataIC50: 4.42E+3nMAssay Description:Inhibition of recombinant human CETP mediated transfer of [3H]cholesteryl ester from HDL to LDLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50101000(3-((biphenyl-3-ylmethyl)(3-phenoxyphenyl)amino)-1,...)
Affinity DataIC50: 4.42E+3nMAssay Description:Inhibition of CETPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Rabbit)
Al-Zaytoonah Private University of Jordan

Curated by ChEMBL
LigandPNGBDBM50101000(3-((biphenyl-3-ylmethyl)(3-phenoxyphenyl)amino)-1,...)
Affinity DataIC50: 4.42E+3nMAssay Description:Inhibition of CETP in rabbit serum after 1 hr by fluorescent cholesteryl esters transfer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed