BDBM50101097 CHEMBL3325959

SMILES CN[C@]1(CC[C@@]2(CC1)OCCc1c2[nH]c2ccc(F)cc12)c1ccccc1

InChI Key InChIKey=AMXGKMSRYLZAEO-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50101097   

TargetMu-type opioid receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM50101097(CHEMBL3325959)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]naloxone from human MOP receptor expressed in CHO-K1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM50101097(CHEMBL3325959)
Affinity DataEC50:  2.60nMAssay Description:Agonist activity at human recombinant MOP receptor expressed in CHO-K1 cells assessed as stimulation of [35S]GTPgammaS binding by scintillation proxi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM50101097(CHEMBL3325959)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandPNGBDBM50101097(CHEMBL3325959)
Affinity DataEC50:  60nMAssay Description:Agonist activity at human recombinant NOP receptor expressed in CHO-K1 cells assessed as stimulation of [35S]GTPgammaS binding by scintillation proxi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed