BDBM50101249 CHEMBL301371::{2-[(1S,3R)-3-Benzo[1,3]dioxol-5-yl-6-ethoxy-2-(1H-tetrazol-5-yl)-2,3-dihydro-1H-isoindol-1-yl]-5-methoxy-phenoxy}-acetic acid

SMILES CCOc1ccc2[C@H](N([C@@H](c2c1)c1ccc(OC)cc1OCC(O)=O)c1nnn[nH]1)c1ccc2OCOc2c1

InChI Key InChIKey=XSIBVUPCSKPMMH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50101249   

TargetEndothelin-1 receptor(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50101249({2-[(1S,3R)-3-Benzo[1,3]dioxol-5-yl-6-ethoxy-2-(1H...)
Affinity DataIC50: 31nMAssay Description:In vitro inhibition of [125I]ET1 binding to CHO cells expressing recombinant human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed