BDBM50101252 CHEMBL432499::[(1R,3R)-1-Benzo[1,3]dioxol-5-yl-3-(2-carboxymethoxy-4-methoxy-phenyl)-5-ethoxy-1,3-dihydro-isoindol-2-yl]-oxo-acetic acid

SMILES CCOc1ccc2[C@H](N([C@H](c2c1)c1ccc(OC)cc1OCC(O)=O)C(=O)C(O)=O)c1ccc2OCOc2c1

InChI Key InChIKey=IRLDCHQLFYENIF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50101252   

TargetEndothelin-1 receptor(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50101252([(1R,3R)-1-Benzo[1,3]dioxol-5-yl-3-(2-carboxymetho...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of [125I]ET1 binding to CHO cells expressing recombinant human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed