BDBM50101331 CHEMBL3329621

SMILES CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(CNC(=O)C[C@H](OC1=O)\C=C\CCSSCC\C=C\[C@@H]1CC(=O)NCc3nc(cs3)C3=N[C@@](C)(CS3)C(=O)N[C@@H](C(C)C)C(=O)O1)n2

InChI Key InChIKey=VXQMEGLYMWVBHB-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50101331   

TargetHistone deacetylase 2(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50101331(CHEMBL3329621)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of HDAC2 (unknown origin) incubated for 30 mins in presence of BSA and DTT by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50101331(CHEMBL3329621)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of HDAC1 (unknown origin) incubated for 30 mins in presence of BSA and DTT by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50101331(CHEMBL3329621)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of HDAC3 (unknown origin) incubated for 30 mins in presence of BSA and DTT by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50101331(CHEMBL3329621)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of HDAC11 (unknown origin) incubated for 3 hrs in presence of BSA and DTT by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50101331(CHEMBL3329621)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of HDAC10 (unknown origin) incubated for 30 mins in presence of BSA and DTT by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50101331(CHEMBL3329621)
Affinity DataIC50: 61nMAssay Description:Inhibition of HDAC6 (unknown origin) incubated for 30 mins in presence of BSA and DTT by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed