BDBM50101660 5-Acetyl-4-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propylamino}-2-methyl-6-phenyl-2H-pyridazin-3-one::CHEMBL80260

SMILES COc1ccccc1N1CCN(CCCNc2c(C(C)=O)c(nn(C)c2=O)-c2ccccc2)CC1

InChI Key InChIKey=NAYUKRZMBPSGCB-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50101660   

TargetAlpha-1A adrenergic receptor(Human)
Istituto Chimico Farmaceutico E Tossicologico

Curated by ChEMBL
LigandPNGBDBM50101660(5-Acetyl-4-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl...)
Affinity DataKi:  1.51nMAssay Description:Binding affinity towards human cloned alpha-1A-adrenoceptor using [3H]prazosin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Istituto Chimico Farmaceutico E Tossicologico

Curated by ChEMBL
LigandPNGBDBM50101660(5-Acetyl-4-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl...)
Affinity DataKi:  4.32nMAssay Description:Binding affinity towards human cloned alpha-1D-adrenoceptor using [3H]prazosin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Istituto Chimico Farmaceutico E Tossicologico

Curated by ChEMBL
LigandPNGBDBM50101660(5-Acetyl-4-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl...)
Affinity DataKi:  20.3nMAssay Description:Binding affinity towards human cloned alpha-1B-adrenoceptor using [3H]prazosin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Istituto Chimico Farmaceutico E Tossicologico

Curated by ChEMBL
LigandPNGBDBM50101660(5-Acetyl-4-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl...)
Affinity DataKi:  135nMAssay Description:Binding affinity towards human cloned 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed