BDBM50101712 CHEMBL300375::{3-[Benzyl-(2-methoxy-ethoxycarbonyl)-amino]-cyclohexyl}-(4'-methoxy-biphenyl-4-sulfonylamino)-acetic acid

SMILES COCCOC(=O)N(Cc1ccccc1)C1CCCC(C1)C(NS(=O)(=O)c1ccc(cc1)-c1ccc(OC)cc1)C(O)=O

InChI Key InChIKey=YHTDLXCRQOJRHH-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50101712   

TargetMatrilysin(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101712({3-[Benzyl-(2-methoxy-ethoxycarbonyl)-amino]-cyclo...)
Affinity DataIC50: 6.34E+3nMAssay Description:In vitro inhibitory concentration against Matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101712({3-[Benzyl-(2-methoxy-ethoxycarbonyl)-amino]-cyclo...)
Affinity DataIC50: 16nMAssay Description:In vitro inhibitory concentration against Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101712({3-[Benzyl-(2-methoxy-ethoxycarbonyl)-amino]-cyclo...)
Affinity DataIC50: 6nMAssay Description:In vitro inhibitory concentration against Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101712({3-[Benzyl-(2-methoxy-ethoxycarbonyl)-amino]-cyclo...)
Affinity DataIC50: 210nMAssay Description:In vitro inhibitory concentration against Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101712({3-[Benzyl-(2-methoxy-ethoxycarbonyl)-amino]-cyclo...)
Affinity DataIC50: 5.35E+3nMAssay Description:In vitro inhibitory concentration against Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed