BDBM50101720 (1,4-Dioxa-spiro[4.5]dec-7-yl)-(4'-methoxy-biphenyl-4-sulfonylamino)-acetic acid::CHEMBL61017

SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)NC(C1CCCC2(C1)OCCO2)C(O)=O

InChI Key InChIKey=KVNBSMBKXVJFRN-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50101720   

TargetCollagenase 3(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101720((1,4-Dioxa-spiro[4.5]dec-7-yl)-(4'-methoxy-bipheny...)
Affinity DataIC50: 13nMAssay Description:In vitro inhibitory concentration against Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101720((1,4-Dioxa-spiro[4.5]dec-7-yl)-(4'-methoxy-bipheny...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibitory concentration against Matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101720((1,4-Dioxa-spiro[4.5]dec-7-yl)-(4'-methoxy-bipheny...)
Affinity DataIC50: 3.78E+3nMAssay Description:In vitro inhibitory concentration against Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101720((1,4-Dioxa-spiro[4.5]dec-7-yl)-(4'-methoxy-bipheny...)
Affinity DataIC50: 9nMAssay Description:In vitro inhibitory concentration against Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101720((1,4-Dioxa-spiro[4.5]dec-7-yl)-(4'-methoxy-bipheny...)
Affinity DataIC50: 630nMAssay Description:In vitro inhibitory concentration against Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed