BDBM50101723 (1,5-Dioxa-spiro[5.5]undec-9-yl)-((S)-4'-methoxy-biphenyl-4-sulfonylamino)-acetic acid::CHEMBL58553

SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N[C@H](C1CCC2(CC1)OCCCO2)C(O)=O

InChI Key InChIKey=WKYNDNVMBNENDU-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50101723   

TargetCollagenase 3(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101723((1,5-Dioxa-spiro[5.5]undec-9-yl)-((S)-4'-methoxy-b...)
Affinity DataIC50: 36nMAssay Description:In vitro inhibitory concentration against Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101723((1,5-Dioxa-spiro[5.5]undec-9-yl)-((S)-4'-methoxy-b...)
Affinity DataIC50: 7nMAssay Description:In vitro inhibitory concentration against Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101723((1,5-Dioxa-spiro[5.5]undec-9-yl)-((S)-4'-methoxy-b...)
Affinity DataIC50: 2.32E+3nMAssay Description:In vitro inhibitory concentration against Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101723((1,5-Dioxa-spiro[5.5]undec-9-yl)-((S)-4'-methoxy-b...)
Affinity DataIC50: 5.00E+3nMAssay Description:In vitro inhibitory concentration against Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101723((1,5-Dioxa-spiro[5.5]undec-9-yl)-((S)-4'-methoxy-b...)
Affinity DataIC50: 2.41E+4nMAssay Description:In vitro inhibitory concentration against Matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed