BDBM50101724 ((S)-4'-Methoxy-biphenyl-4-sulfonylamino)-(4-oxo-cyclohexyl)-acetic acid::CHEMBL59337

SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N[C@H](C1CCC(=O)CC1)C(O)=O

InChI Key InChIKey=KLFOAKCPAGOTNG-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50101724   

TargetCollagenase 3(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101724(((S)-4'-Methoxy-biphenyl-4-sulfonylamino)-(4-oxo-c...)
Affinity DataIC50: 200nMAssay Description:In vitro inhibitory concentration against Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101724(((S)-4'-Methoxy-biphenyl-4-sulfonylamino)-(4-oxo-c...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibitory concentration against Matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101724(((S)-4'-Methoxy-biphenyl-4-sulfonylamino)-(4-oxo-c...)
Affinity DataIC50: 47nMAssay Description:In vitro inhibitory concentration against Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101724(((S)-4'-Methoxy-biphenyl-4-sulfonylamino)-(4-oxo-c...)
Affinity DataIC50: 8.95E+3nMAssay Description:In vitro inhibitory concentration against Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101724(((S)-4'-Methoxy-biphenyl-4-sulfonylamino)-(4-oxo-c...)
Affinity DataIC50: 4.70E+3nMAssay Description:In vitro inhibitory concentration against Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed