BDBM50101730 CHEMBL59472::{3-[(Z)-tert-Butoxyimino]-cyclohexyl}-(4'-methoxy-biphenyl-4-sulfonylamino)-acetic acid

SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)NC(C1CCC\C(C1)=N\OC(C)(C)C)C(O)=O

InChI Key InChIKey=DHMHJSLNCAYKRH-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50101730   

TargetMatrilysin(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101730({3-[(Z)-tert-Butoxyimino]-cyclohexyl}-(4'-methoxy-...)
Affinity DataIC50: 5.15E+3nMAssay Description:In vitro inhibitory concentration against Matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101730({3-[(Z)-tert-Butoxyimino]-cyclohexyl}-(4'-methoxy-...)
Affinity DataIC50: 320nMAssay Description:In vitro inhibitory concentration against Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101730({3-[(Z)-tert-Butoxyimino]-cyclohexyl}-(4'-methoxy-...)
Affinity DataIC50: 3nMAssay Description:In vitro inhibitory concentration against Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101730({3-[(Z)-tert-Butoxyimino]-cyclohexyl}-(4'-methoxy-...)
Affinity DataIC50: 4.11E+3nMAssay Description:In vitro inhibitory concentration against Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101730({3-[(Z)-tert-Butoxyimino]-cyclohexyl}-(4'-methoxy-...)
Affinity DataIC50: 7nMAssay Description:In vitro inhibitory concentration against Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed