BDBM50101765 (2S)-2-{[(benzyloxy)carbonyl]amino}-3-[(5-{2-[(1,4,5,6-tetrahydropyrimidin-2-yl)carbamoyl]ethyl}thiophen-2-yl)formamido]propanoic acid::CHEMBL304217

SMILES OC(=O)[C@H](CNC(=O)c1ccc(CCC(=O)NC2=NCCCN2)s1)NC(=O)OCc1ccccc1

InChI Key InChIKey=LUSHAVDQHKTOOU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50101765   

TargetIntegrin alpha-V/beta-3(Human)
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50101765((2S)-2-{[(benzyloxy)carbonyl]amino}-3-[(5-{2-[(1,4...)
Affinity DataIC50: 63nMAssay Description:Concentration required to reduce binding of human 293 cell attachment to immobilized vitronectin receptor (Vn/293) by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50101765((2S)-2-{[(benzyloxy)carbonyl]amino}-3-[(5-{2-[(1,4...)
Affinity DataIC50: 7nMAssay Description:Concentration required to reduce binding of Kistrin to Vitronectin receptor (alpha V beta 3) by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50101765((2S)-2-{[(benzyloxy)carbonyl]amino}-3-[(5-{2-[(1,4...)
Affinity DataIC50: 4.50E+3nMAssay Description:Concentration required to reduce binding of fibrinogen (Fg) to alpha IIb beta-3 integrin by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed