BDBM50102069 (3-Chloro-4-fluoro-phenyl)-[7-methoxy-6-(2-methylamino-ethoxy)-quinazolin-4-yl]-amine::CHEMBL293090

SMILES CNCCOc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OC

InChI Key InChIKey=MCLWOTRQSAKXBH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50102069   

TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50102069((3-Chloro-4-fluoro-phenyl)-[7-methoxy-6-(2-methyla...)
Affinity DataIC50: 8nMAssay Description:In vitro inhibitory activity against Epidermal growth factor receptor (EGFR-TK) from A431 vulval squamous carcinoma cells using TKI assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed