BDBM50102083 (3-Chloro-4-fluoro-phenyl)-{7-methoxy-6-[2-(4-methyl-piperazin-1-yl)-ethoxy]-quinazolin-4-yl}-amine::CHEMBL300791

SMILES COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCN1CCN(C)CC1

InChI Key InChIKey=UEWRHTSERXIBRC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50102083   

TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50102083((3-Chloro-4-fluoro-phenyl)-{7-methoxy-6-[2-(4-meth...)
Affinity DataIC50: 10nMAssay Description:In vitro inhibitory activity against Epidermal growth factor receptor (EGFR-TK) from A431 vulval squamous carcinoma cells using TKI assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed