BDBM50102084 CHEMBL57892::[6-(2-tert-Butylamino-ethoxy)-7-methoxy-quinazolin-4-yl]-(3-chloro-4-fluoro-phenyl)-amine

SMILES COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCNC(C)(C)C

InChI Key InChIKey=CMKLELUFUHIGLT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50102084   

TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50102084([6-(2-tert-Butylamino-ethoxy)-7-methoxy-quinazolin...)
Affinity DataIC50: 100nMAssay Description:In vitro inhibitory activity against Epidermal growth factor receptor (EGFR-TK) from A431 vulval squamous carcinoma cells using TKI assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed