BDBM50102154 1-{4-[4-(4-Chloro-phenyl)-piperazin-1-yl]-4-oxo-butyl}-2-(4-fluoro-benzylsulfanyl)-5-(1-methyl-1H-pyrazol-4-ylmethyl)-1H-pyrimidin-4-one::CHEMBL57132

SMILES Cn1cc(Cc2cn(CCCC(=O)N3CCN(CC3)c3ccc(Cl)cc3)c(SCc3ccc(F)cc3)nc2=O)cn1

InChI Key InChIKey=DMGXDLAAACKZRH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50102154   

TargetPlatelet-activating factor acetylhydrolase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50102154(1-{4-[4-(4-Chloro-phenyl)-piperazin-1-yl]-4-oxo-bu...)
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against human lipoprotein associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed