BDBM50102156 1-{2-[4-(4-Acetyl-phenyl)-piperazin-1-yl]-2-oxo-ethyl}-2-(4-fluoro-benzylsulfanyl)-5-pyrimidin-5-ylmethyl-1H-pyrimidin-4-one::CHEMBL57720

SMILES CC(=O)c1ccc(cc1)N1CCN(CC1)C(=O)Cn1cc(Cc2cncnc2)c(=O)nc1SCc1ccc(F)cc1

InChI Key InChIKey=JWCGHIBPLJIFRS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50102156   

TargetPlatelet-activating factor acetylhydrolase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50102156(1-{2-[4-(4-Acetyl-phenyl)-piperazin-1-yl]-2-oxo-et...)
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against human lipoprotein associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed