BDBM50102186 (Difluoro-phenyl-methyl)-phosphonic acid::CHEMBL57974::Difluoro-phenyl-methanephosphonic acid anion

SMILES OP(O)(=O)C(F)(F)c1ccccc1

InChI Key InChIKey=LEHCDHHLEVYQNS-UHFFFAOYSA-N

Data  2 KI  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50102186   

TargetReceptor-type tyrosine-protein phosphatase C(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50102186((Difluoro-phenyl-methyl)-phosphonic acid | Difluor...)
Affinity DataIC50: 1.00E+7nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLaforin(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50102186((Difluoro-phenyl-methyl)-phosphonic acid | Difluor...)
Affinity DataIC50: 8.38E+6nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDual specificity protein phosphatase 10(Mus musculus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50102186((Difluoro-phenyl-methyl)-phosphonic acid | Difluor...)
Affinity DataIC50: 8.23E+6nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50102186((Difluoro-phenyl-methyl)-phosphonic acid | Difluor...)
Affinity DataIC50: 7.99E+6nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50102186((Difluoro-phenyl-methyl)-phosphonic acid | Difluor...)
Affinity DataIC50: 5.73E+6nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50102186((Difluoro-phenyl-methyl)-phosphonic acid | Difluor...)
Affinity DataIC50: 3.27E+6nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50102186((Difluoro-phenyl-methyl)-phosphonic acid | Difluor...)
Affinity DataIC50: 4.85E+6nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50102186((Difluoro-phenyl-methyl)-phosphonic acid | Difluor...)
Affinity DataIC50: 2.22E+6nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50102186((Difluoro-phenyl-methyl)-phosphonic acid | Difluor...)
Affinity DataIC50: 3.21E+6nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50102186((Difluoro-phenyl-methyl)-phosphonic acid | Difluor...)
Affinity DataIC50: 2.86E+6nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50102186((Difluoro-phenyl-methyl)-phosphonic acid | Difluor...)
Affinity DataKi:  2.50E+3nMAssay Description:Inhibitory activity against Yersinia Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMandelate racemase(Pseudomonas putida (g-Proteobacteria))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50102186((Difluoro-phenyl-methyl)-phosphonic acid | Difluor...)
Affinity DataKi:  1.20E+7nMpH: 7.5Assay Description:Inhibition constant against Mandelate racemase from Pseudomonas putida at pH 7.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed