BDBM50102510 2,4-Diamino-5-{3-[3-[2-acetyloxy)ethyl]-3-(4-pyridin-4-ylmethyl)triazen-1-yl]-4-chlorophenyl}-6-ethylpyrimidine::CHEMBL87730

SMILES CCc1nc(N)nc(N)c1-c1ccc(Cl)c(c1)\N=N\N(CCOC(C)=O)Cc1ccncc1

InChI Key InChIKey=QVZMTKPFUHBAMZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50102510   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50102510(2,4-Diamino-5-{3-[3-[2-acetyloxy)ethyl]-3-(4-pyrid...)
Affinity DataIC50: 640nMAssay Description:Inhibitory activity against dihydrofolate reductase DHFR in Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mycobacterium avium)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50102510(2,4-Diamino-5-{3-[3-[2-acetyloxy)ethyl]-3-(4-pyrid...)
Affinity DataIC50: 2.03E+3nMAssay Description:Inhibitory activity against dihydrofolate reductase DHFR in Mycobacterium aviumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50102510(2,4-Diamino-5-{3-[3-[2-acetyloxy)ethyl]-3-(4-pyrid...)
Affinity DataIC50: 6.19E+3nMAssay Description:Inhibitory activity against dihydrofolate reductase DHFR in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed