BDBM50102522 2,4-Diamino-5-{3-[3-[2-acetyloxy)ethyl]-3-(3-nitro benzyl)triazen-1-yl]-4-chlorophenyl}-6-ethylpyrimidine::CHEMBL88004

SMILES CCc1nc(N)nc(N)c1-c1ccc(Cl)c([N-]N=[N+](CCOC(C)=O)Cc2cccc(c2)[N+]([O-])=O)c1

InChI Key InChIKey=IMIBWADXFTWNOQ-UHFFFAOYSA-O

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50102522   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50102522(2,4-Diamino-5-{3-[3-[2-acetyloxy)ethyl]-3-(3-nitro...)
Affinity DataIC50: 830nMAssay Description:Inhibitory activity against dihydrofolate reductase DHFR in Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50102522(2,4-Diamino-5-{3-[3-[2-acetyloxy)ethyl]-3-(3-nitro...)
Affinity DataIC50: 1.61E+3nMAssay Description:Inhibitory activity against dihydrofolate reductase DHFR in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mycobacterium avium)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50102522(2,4-Diamino-5-{3-[3-[2-acetyloxy)ethyl]-3-(3-nitro...)
Affinity DataIC50: 3.69E+3nMAssay Description:Inhibitory activity against dihydrofolate reductase DHFR in Mycobacterium aviumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed