BDBM50102678 CHEMBL3343058

SMILES CCNC(=O)Nc1ccc(NC(=O)c2cc(OC)cc(c2)-c2c[nH]c(=O)[nH]c2=O)cc1

InChI Key InChIKey=ZDYHHMHXNVBIAM-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50102678   

TargetAurora kinase B(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50102678(CHEMBL3343058)
Affinity DataIC50: 1.81E+4nMAssay Description:Inhibition of human AURKB incubated for 20 mins prior to MgCl2 addition measured after 90 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50102678(CHEMBL3343058)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human JAK1 incubated for 20 mins prior to MgCl2 addition measured after 90 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50102678(CHEMBL3343058)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human JAK2 incubated for 20 mins prior to MgCl2 addition measured after 90 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50102678(CHEMBL3343058)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human JAK3 incubated for 20 mins prior to MgCl2 addition measured after 90 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50102678(CHEMBL3343058)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CDK1 incubated for 20 mins prior to MgCl2 addition measured after 90 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50102678(CHEMBL3343058)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CDK2 incubated for 20 mins prior to MgCl2 addition measured after 90 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50102678(CHEMBL3343058)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CDK9 incubated for 20 mins prior to MgCl2 addition measured after 90 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetBifunctional protein GlmU(Escherichia coli (strain K12))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50102678(CHEMBL3343058)
Affinity DataIC50: 970nMAssay Description:Inhibition of Escherichia coli ATCC 27325 GlmU expressed in Escherichia coli HMS174(DE3) incubated for 15 mins prior to MgCl2 addition measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50102678(CHEMBL3343058)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human IRAK4 incubated for 20 mins prior to MgCl2 addition measured after 90 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50102678(CHEMBL3343058)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human IRAK1 incubated for 20 mins prior to MgCl2 addition measured after 90 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2016
Entry Details Article
PubMed