BDBM50103015 (S)-5-Amino-2-[(S)-2-{3-[1-(2,6-dichloro-benzyl)-3-pyrrolidin-1-ylmethyl-1H-indol-6-yl]-ureido}-3-(3,4-difluoro-phenyl)-propionylamino]-pentanoic acid benzylamide::CHEMBL67308

SMILES NCCC[C@H](NC(=O)[C@H](Cc1ccc(F)c(F)c1)NC(=O)Nc1ccc2c(CN3CCCC3)cn(Cc3c(Cl)cccc3Cl)c2c1)C(=O)NCc1ccccc1

InChI Key InChIKey=WFYIZTPIVKULTE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50103015   

TargetProteinase-activated receptor 1(Human)
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103015((S)-5-Amino-2-[(S)-2-{3-[1-(2,6-dichloro-benzyl)-3...)
Affinity DataIC50: 100nMAssay Description:In vitro inhibition of human platelet aggregation induced by SFLLRN-NH2 (at a concentration of 2 uM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103015((S)-5-Amino-2-[(S)-2-{3-[1-(2,6-dichloro-benzyl)-3...)
Affinity DataIC50: 100nMAssay Description:In vitro inhibition of human platelet aggregation induced by SFLLRN-NH2 (at a concentration of 2 uM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103015((S)-5-Amino-2-[(S)-2-{3-[1-(2,6-dichloro-benzyl)-3...)
Affinity DataIC50: 500nMAssay Description:In vitro displacement of [3H]S-(p-F-Phe)-homoarginine-K Y-NH2 (at a concentration of 10 uM) from thrombin receptor (PAR-1) on the membranes of CHRF-2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed