BDBM50103555 CHEMBL3358002

SMILES C[C@@H]1CN(CCN1c1ncc(OCc2ccc(OS(C)(=O)=O)cc2F)cn1)c1nnc(o1)C(F)(F)F

InChI Key InChIKey=UTOPRESBQKAWRB-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50103555   

LigandPNGBDBM50103555(CHEMBL3358002)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human ERG by patch clamp based electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103555(CHEMBL3358002)
Affinity DataEC50:  42nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103555(CHEMBL3358002)
Affinity DataEC50:  4nMAssay Description:Agonist activity at human GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed