BDBM50103562 CHEMBL3357995

SMILES C[C@@H]1CN(CCN1c1ncc(OCc2ccc(cc2C#N)S(C)(=O)=O)cn1)c1nnc(o1)C(F)(F)F

InChI Key InChIKey=YPZUCWRGPJUFCO-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50103562   

LigandPNGBDBM50103562(CHEMBL3357995)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of human ERG by patch clamp based electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103562(CHEMBL3357995)
Affinity DataEC50:  1.98E+3nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103562(CHEMBL3357995)
Affinity DataEC50:  55nMAssay Description:Agonist activity at human GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed