BDBM50103602 CHEMBL3526396

SMILES C[C@@]12Nc3ccccc3[C@]1(O)CCN2Cc1ccc(\C=C\C(N)=O)cc1

InChI Key InChIKey=GSUOTZHCHGUHCC-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50103602   

TargetHistone deacetylase 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50103602(CHEMBL3526396)
Affinity DataIC50: 930nMAssay Description:Inhibition of HDAC3 (unknown origin) expressed in HEK293 cells using [3H]acetylated human histone H4 peptide as substrate by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50103602(CHEMBL3526396)
Affinity DataIC50: 970nMAssay Description:Inhibition of HDAC1 (unknown origin) expressed in HEK293 cells using [3H]acetylated human histone H4 peptide as substrate by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2016
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50103602(CHEMBL3526396)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of HDAC4 (unknown origin) expressed in HEK293 cells using [3H]acetylated human histone H4 peptide as substrate by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2016
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50103602(CHEMBL3526396)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of HDAC6 (unknown origin) expressed in HEK293 cells using [3H]acetylated human histone H4 peptide as substrate by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2016
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50103602(CHEMBL3526396)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of flag-tagged HDAC2 (unknown origin) expressed in SF21 cells using [3H]acetylated human histone H4 peptide as substrate by scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2016
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50103602(CHEMBL3526396)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of his-strep-tagged HDAC8 (unknown origin) expressed in SF9 cells using [3H]acetylated human histone H4 peptide as substrate by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2016
Entry Details Article
PubMed