BDBM50103778 CHEMBL311114::[5-{2-[1-(3-Carbamoyl-4-cyclohexylmethoxy-phenyl)-1-methyl-ethylcarbamoyl]-ethyl}-2-(tetrazol-1-ylmethoxy)-phenyl]-phosphonic acid

SMILES CC(C)(NC(=O)CCc1ccc(OCn2cnnn2)c(c1)P(O)(O)=O)c1ccc(OCC2CCCCC2)c(c1)C(N)=O

InChI Key InChIKey=DWNWEWCPDNAGAA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50103778   

TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103778([5-{2-[1-(3-Carbamoyl-4-cyclohexylmethoxy-phenyl)-...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of binding to Zap70 protein kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103778([5-{2-[1-(3-Carbamoyl-4-cyclohexylmethoxy-phenyl)-...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of binding to Src SH2 domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Yes(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103778([5-{2-[1-(3-Carbamoyl-4-cyclohexylmethoxy-phenyl)-...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of binding to Yes SH2 domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed