BDBM50104156 CHEMBL3594232

SMILES [H][C@@]12C[C@@H](C[C@]1([H])CN(C2)c1nc(C)cc(n1)C(O)=O)c1ccccc1C(F)(F)F

InChI Key InChIKey=XODSGAMMDBEEFN-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50104156   

TargetRetinol-binding protein 4(Human)
Columbia University Medical Center

Curated by ChEMBL
LigandPNGBDBM50104156(CHEMBL3594232)
Affinity DataIC50: 13nMAssay Description:Displacement of [3H]-retinol from RBP4 (unknown origin) by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Columbia University Medical Center

Curated by ChEMBL
LigandPNGBDBM50104156(CHEMBL3594232)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG expressed in HEK293 cells by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2016
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Columbia University Medical Center

Curated by ChEMBL
LigandPNGBDBM50104156(CHEMBL3594232)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2016
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Columbia University Medical Center

Curated by ChEMBL
LigandPNGBDBM50104156(CHEMBL3594232)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Columbia University Medical Center

Curated by ChEMBL
LigandPNGBDBM50104156(CHEMBL3594232)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Columbia University Medical Center

Curated by ChEMBL
LigandPNGBDBM50104156(CHEMBL3594232)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2016
Entry Details Article
PubMed
TargetRetinol-binding protein 4(Human)
Columbia University Medical Center

Curated by ChEMBL
LigandPNGBDBM50104156(CHEMBL3594232)
Affinity DataIC50: 44nMAssay Description:Inhibition of retinol-induced interaction of bacterially expressed MBP-tagged RBP4 (unknown origin) with Eu3+ cryptate labeled TTR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2016
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Albany College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50104156(CHEMBL3594232)
Affinity DataIC50: 3.60E+3nMAssay Description:Agonist activity at PPARgamma (unknown origin) assessed as inhibition by agonist-induced corepressor NCoR release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed