BDBM50104334 1-(2-Chloro-2-phenyl-ethyl)-4-phenethylamino-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester::CHEMBL432950::ethyl 1-(2-chloro-2-phenylethyl)-4-(phenethylamino)-1H-pyrazolo[3,4-b]pyridine-5-carboxylate

SMILES CCOC(=O)c1cnc2n(CC(Cl)c3ccccc3)ncc2c1NCCc1ccccc1

InChI Key InChIKey=HIQBGSUBPJSVCZ-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50104334   

TargetAdenosine receptor A1(Bovine)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50104334(ethyl 1-(2-chloro-2-phenylethyl)-4-(phenethylamino...)
Affinity DataKi:  50nMAssay Description:Binding affinity against bovine Adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Bovine)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50104334(ethyl 1-(2-chloro-2-phenylethyl)-4-(phenethylamino...)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]CHA from Adenosine A1 receptor in bovine cortical membrane expressed as KiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Bovine)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50104334(ethyl 1-(2-chloro-2-phenylethyl)-4-(phenethylamino...)
Affinity DataKi:  50nMAssay Description:Binding affinity to Adenosine A1 receptor in bovine cortical membranes by [3H]N6-cyclohexyl adenosine displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Bovine)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50104334(ethyl 1-(2-chloro-2-phenylethyl)-4-(phenethylamino...)
Affinity DataKi:  56nMAssay Description:Displacement of [3H]DPCPX from Adenosine A1 receptor of bovine cortical membranes with 1 mM GTPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Bovine)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50104334(ethyl 1-(2-chloro-2-phenylethyl)-4-(phenethylamino...)
Affinity DataKi:  69.7nMAssay Description:Displacement of [3H]DPCPX from Adenosine A1 receptor of bovine cortical membranes without GTPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50104334(ethyl 1-(2-chloro-2-phenylethyl)-4-(phenethylamino...)
Affinity DataKi:  73nMAssay Description:Binding affinity against rat Adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed